Pro-Stat® Sugar Free Advanced Wound Care is a high calorie, complete protein liquid, with added Arginine, Citrulline, Cystine, Zinc, and Vitamin C. It is the only wound care supplement to contain Citrulline, a precursor to Arginine increasing nitric oxide production, (thus increasing blood flow to the wound and collagen formation).
This uniquely engineered combination of ingredients provides a synergistic approach to wound healing while reducing the need for multiple supplements and added cost.
Nitric oxide is essential for wound healing. It increases blood and oxygen flow to the wound, increases collagen formation, reduces inflammation and kills bacteria all helping to close wounds.
Arginine is the only producer of nitric oxide, however, 40% of ingested arginine is broken down by the intestine and liver making less available for nitric oxide production.
Citrulline, prevalent in watermelon, converts to arginine but is not broken down like arginine. This conversion allows for more nitric oxide production thus facilitating healing. Citrulline has been shown to be more effective than arginine in raising plasma arginine levels.
Pro-Stat AWC contains enriched collagen protein providing a naturally occurring high nitrogen mix of all essential, conditionally essential and non-essential amino acids that is hydrolyzed (pre-digested) using papain, a fruit enzyme.
Pressure ulcers, also known as bedsores, can significantly diminish quality of life and require substantial cost to remedy.
It is estimated that 1 to 3 million people in the US develop pressure ulcers each year. Across all settings the estimates of pressure ulcers prevalence in the US is 10% to 18% in acute care, 2.3% to 28% in long term care, and 0% to 29% in home care. The European Pressure Ulcer Advisory Panel and National Pressure Ulcer Advisory Panel; Treatment of pressure ulcers: Quick Reference Guide. Washington DC: National Pressure Ulcer Advisory Panel; 2009 indicates that patients with pressure ulcers need 30 to 35 kilocalories and 1.25 to 1.5 grams of protein per kilogram of body weight daily and increased requirements for L-Arginine, L-Cystine, Vitamin C, and Zinc.
Each one fluid ounce (30 ml) serving of Pro-Stat Suger Free AWC with Citrulline contains: 17 grams of protein - 15 grams protein from enriched collagen (tryptophan and cystine added) and 2.0 grams added L-Arginine. Wheat, Lactose and Gluten Free.
Indications for Use:
For Pressure Ulcers, Wounds (Multiple, Severe, Chronic,
Surgical), Diabetic Foot Ulcers, Venous Stasis Ulcers, and Burns.
Many patients in long-term health care facilities develop pressure ulcers, or bed sores.
Pro-Stat is naturally rich in Arginine, Glycine, Proline and Hydroxyproline, high nitrogen donor amino acids that are a critical factor in replenishing depleted protein stores and accelerating tissue healing in patients with pressure ulcers.
The physiological demands of repair and recovery from wounds, burns, sepsis and trauma (including surgical trauma) often require greater amounts of L-arginine than can be synthesized by the body. Additional dietary intake of L-arginine is indicated when these conditions are present:
- Needed to promote protein regeneration and the healing of wounds.
- Essential when the body is under stress or in an injured state.
- Conditionally essential, particularly during growth, illness or metabolic stress when the body’s production may be insufficient to meet demands.
- Improves markers of wound healing with greater protein and hydroxyproline in the wound bed and promotion of positive nitrogen balance.
Citrulline supplementation is an efficient alternative to oral administration of Arginine in raising its plasma levels and modulating Nitric Oxide production. A non-standard amino acid found in watermelon.
Cystine controls and promotes positive nitrogen balance for minimizing muscle breakdown and rebuilding lean body mass (LBM).
Ascorbic Acid (Vitamin C)
Vitamin C is essential for wound healing and for the repair and maintenance of cartilage, bones, and teeth. Vitamin C deficiency can lead to a decreased wound-healing rate. The body does not manufacture vitamin C on its own, nor does it store it.
- Promotes collagen synthesis and enhances activation of leukocytes and macrophages to the wound site
- Promotes healthy cell development, proper calcium absorption, normal tissue growth and repair - such as healing of wounds and burns.
- Required for the growth and repair of tissues in all parts of the body.
- Necessary to form collagen, an important protein used to make skin, scar tissue, tendons, ligaments, and blood vessels.
Zinc has been shown to be beneficial to wound healing and zinc deficiency has been associated with delayed wound healing.
- Assists in immune function and interacts with platelets in blood clotting.
- When zinc supplements are given to individuals with low zinc levels, the numbers of T-cell lymphocytes circulating in the blood increase and the ability of lymphocytes to fight infection improves.
Does Pro-Stat® need to be mixed?
No. Pro-Stat® is in liquid form and ready to use, shelf stable liquid.
Can diabetics use Pro-Stat®?
Pro-Stat® 64 is sugar and carbohydrate free. Pro-Stat® 101, AWC, RC and Profile contain fructose, a low glycemic sweetener acceptable for diabetics. Diabetic should continue their regular their regular blood glucose monitoring and consult with their doctor. For those following a carbohydrate restricted diet, a serving of Pro-Stat® 101, AWC, RC or Profile™ has fewer grams of carbohydrates than a serving of juice.
How is Pro-Stat® administered?
a. Orally; Pro-Stat may be served alone without additional mixing.
b. Orally; mixed with other commercial nutritional supplements and shakes.
c. Orally; mixed into soft foods or beverages.
d. Through a feeding tube
Pro-Stat mixes easily without clumping or decreasing the food's palatability. Suggested foods are: Canned Pineapple & Pears, Applesauce, Farina, Vanilla/Cinnamon Instant Oatmeal and Apple/Cinnamon Instant Oatmeal.
Suggested beverages are: juice, soda, coffee and tea.
Do not refrigerate, cook, or reheat foods/beverages mixed with Pro-Stat.
Which Pro-Stat® is best for advanced wounds?
Pro-Stat AWC (Advanced Wound Care) is formulated for advanced wounds (Stage III and IV.) It provides 17 grams/protein and 108 K/cal per 30ml, with 3.3 grams L-Arginine, 10mg elemental Zinc and 175 mg Vitamin C. Recommended dosage is three times daily for 4-6 weeks, or the duration of the facility’s Zinc protocol. If the wound has not healed, transition to Pro-Stat 64 or 101 three times daily until healed. A maintenance dose of Pro-Stat 64 or 101 once daily may reduce the risk of pressure ulcer recurrence (which can be as high as 80% for previous wound sites).
Which Pro-Stat® is best for ESRD/CHD patients?
Pro-Stat® RC (Renal Care) is a protein/vitamin supplement specifically formulated for the ESRD/CHD patient. A 30ml dose contains 15grams of complete protein and 60 K/cal plus Thiamin, Riboflavin, Niacin, Pantothenic Acid, Pyridoxine, Cobalamin, Folic Acid, Biotin, Ascorbic Acid, Zinc and FOS ( for prebiotic intestinal health). Pro-Stat RC provides for the increased protein and vitamin needs of the dialysis patient without the added fluid required to reconstitute powdered protein supplements. It is sugar and carbohydrate free.
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